[1] The perennial plant is native to the Atlantic Forest ecoregions of eastern Brazil . Side effects of Ewe eje (Justicia carnea leaf Side Effects) Ewe eje is safe and healthy for consumption. . I do hope that after reading through this article, you would plan to start cultivating this amazing plant specie in your garden. 400). Google Scholar. The present study investigated the antioxidant and in vitro antidiabetic capacities of Justicia carnea aqueous leaf extract (JCAE) using -amylase inhibition model. While vitamin A maintains good vision, vitamin B are good for cellular functions such as metabolisms and energy production, and improve brain functioning. How often should it be watered? Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. Whether added to garden beds or pots, the justicia (plant) adds a colorful tropical touch and are easy to grow. Rich on haematological and biochemical parameters in healthy Wistar rats. The plant is transplanted in the spring. From mild to severe order, the graded doses showed distorted renal cortex with collapsed renal glomeruli and dillated capsular spaces. Mr. T.S. Chidubem Olovo is a biochemist and a researcher whose interest is centered on the chemistry of natural products, their pharmacological properties and how using the plant sources can improve human healthy living. Related: The Persian Shield plant is also in the Acanthaceae family. Vitamin B aids in the formation of red blood cells and helps to build tissues. Google Scholar. The presence of blood boosting nutrients such as iron, copper, zinc and vitamin C can help prevent iron-deficiency anaemia and other anemic conditions. et al. View abstract. When there is high cholesterol level in your blood, LDL- and VLDL- cholesterols are being deposited on the arterial wall of blood vessels, thereby blocking free flow of blood and increasing blood pressure. Nutritional Composition of Ewe eje (Justicia carnea leaf). Make sure to follow the package instructions carefully. Cut back after flowering to 2-3 nodes from the ground to keep the plant bushy and promote new blooms. Furthermore, increased MID by the extracts could indicate macrophage formation ability and pathogenic scavenging role. 1958;25(1):192205. Justicia pectoralis might have many different effects in the body. The protein content may help in cellular functions and are building blocks for structural and functional biomolecules. Effects of ethanol leaf extract of Justicia carnea on serum SOD Kidney weight of rats treated with JCEE showed no significant difference with exception in 800mg/kg JCEE that demonstrated significant reduction. All authors read and approved the final draft of the manuscript. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. Ewe eje can also be used to manage abnormalities associated with anaemia and for the treatment and management of diabetics. Mean corpuscular hemoglobin (MCH) and mean corpuscular hemoglobin concentration (MCHC) showed significant (p<0.05) increased at 50mg/kg while doses greater than 100mg/kg showed no significant difference compared to the control. 2023 BioMed Central Ltd unless otherwise stated. Ewe eje is mainly given to persons who want a blood boost such as pregnant women, persons suffering from anemia and other convalescents. View abstract. Pompella A, Visvikis A, Paolicchi A, De Tata V, Casini AF. Clin Phytosci 7, 2 (2021). At the end of the 14th day of administration, the rats were allowed to fast overnight and sacrificed the following morning by anesthetizing each rat in a closed chamber containing drops of chloroform. https://doi.org/10.1186/s40816-020-00234-4, DOI: https://doi.org/10.1186/s40816-020-00234-4. Saunders; 1995. p. 26873. 2. Safety assessment of oral administration of ethanol extract of Justicia carnea leaf in healthy wistar rats: hematology, antioxidative and histology studies. Accept They look terrific in properly shaded outside areas such as porches, patios, driveways, and entryways. Although, medically, it is advised you see your doctor or a physician before using the leaf for medicinal uses. Tissues were stained with haematoxylin and eosin, mounted on glass slides and examined under a standard light microscope. Background: Justicia carnea is a medicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. They are also needed in strong bone formation, and in cellular and neuronal functions. In which ever condition, the blood glucose level increases abnormally. 8-10 Justicia carnea leaves. A total number of forty two (42) male albino rats weighing between 120 and 170g were used in this study. The antioxidants in Justicia carnea helps protect the liver and the heart from toxic agents and free radicals. Consumption of medicinal plants has diverse therapeutic benefits and could also have toxic effect. Briefly, 1.0ml of the sample was mixed with 2ml of TCA-TBA-HCl reagent (0.37% thiobarbituric acid, 15% trichloroacetic acid and 0.24N HCl in 1:1:1) and boiled at 100C in a water bath for 15min. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). They should be watered regularly (once per week), but not overwatered. They range in colors such as red, orange, mauve, magenta, apricot, and pink. Mean lethal dose of the extract was found to be above 5000mg/kg body weight (bw). The findings back up local assertions that they can be. The effects of ethanol extract of J. carnea leaf on total protein concentration and antioxidant system in liver and kidney of normal wistar rat is presented in Table 4. Ani, Onuabuchi & Udedi, Stanley & Asogwa, Kingsley & Enemali, Michael & Onwelumadu, Chigozie & Ikedife, Kenneth. The result of hematology indices is presented in Table3. Luckily, the unique flowers of Jacobinia carnea and its foliage are free from major pest and disease concerns. Superoxide dismutase was carried out using the method of Sun and Zigma [18]. J. Appl. Haematological and biochemical studies on Justicia carnea - PubMed Grows up to 4-6 ft. tall (120-180 cm) and 2-3 ft. wide (60-90 cm). [4].Inflammationinjuries, in an attempt to heal is presented by five cardinal signs of heat (calor), redness (rubor), swelling (tumor), pain (dolor) and loss of function5.Studieshave demonstrated inflammation as being caused by I am a practicing medical doctor, a philosopher, critical thinker, a globalist, a patriot, SEO expert and a patient blogger. View abstract. The significant increase in MDA level at 1200mg/kg might be due to the presence of active secondary metabolites in the extracts that could have acted as prooxidant. View abstract. International Journal of Phytomedicine and Phytotherapy, Clinical Phytoscience The resultant liquid after boiling is usually crimson red. Locklear, T. D., Huang, Y., Frasor, J., Doyle, B. J., Perez, A., Gomez-Laurito, J., and Mahady, G. B. Estrogenic and progestagenic effects of extracts of Justicia pectoralis Jacq., an herbal medicine from Costa Rica used for the treatment of menopause and PMS. Tietz NW. Justicia carnea (ewe eje) is used by pregnant women to boost the production of red blood cells and cure anemia in pregnancy. It helps in replenishing blood lost during period. The shrubby habit of the plant is well-suited for both containers and outside planting. California Privacy Statement, Free radicals and antioxidants in normal physiological functions and human disease. The non significant decrease observed in this study is in consonance with the work of Onyeabo et al., [9] who also reported no significant difference in the relative weights of liver and kidney. Regular intake can reduce your risk of liver diseases like liver cirrhosis, hepatitis and liver inflammation. Acute and chronic toxicity of the aqueous extract of Artemisia afra in rodents. Ethanol extracts of J. carnea leaf increased RBC, hemoglobin and platelet with significant increase (p<0.05) in groups that received higher dose (>500mg/kg b.w) of extract compared to the control. Anaemia is a common blood disorder that affects people of all ages, though people at greater risk are the elderly, young women and infants. The leaves are also rich source of vitamin A, vitamin C, and vitamin E. Another plant with this composition is pumpkin fruit. No observable focal sclerosis of renal glomeruli, capsular spaces around the glomerulus appears normal with distinct layering of renal microcellular structures. Total protein concentration in tissue homogenates were determined using biuret method Tietz [16]. In a pot, pour in a cup of water and bring to a boil. Becoming a contributing member of Gardenia is easy and can be done in just a few minutes. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. They protect our cells from the harmful effects of reactive oxygen species. Sedlak J, Lindsay RH. Wash the Justicia carnea leaves thoroughly to eliminate all forms of insects and dust. These minerals help in boosting blood production, which is why the plant is called ogwu obara (blood medicine) among the Igbo people of Southern Nigeria. Parameter that were determined include total haemoglobin concentration (HGB), packed cell volume (PCV), red blood cell count (RBC), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentration (MCHC), mean corpuscular volume (MCV), white blood cell count (WBC), Lymphocyte count (LYM), MID sized cell (MID), Granulocyte Count (GRM) and platelet count (PLT). In phase two, three rats were separated into 3 groups of one rat per group. It has already been pointed out that this plant is used traditionally to boost blood production among the people of southern Nigeria. Justicia Betonica Herb Uses, Benefits, Cures, Side Effects, Nutrients Afr J Tradit Complement Altern Med. Sun M, Zigma S. An improved spectrophotometer assay of superoxide dismutase based on epinephrine autoxidation. For some, the boiling method is preferred while for others, soaking in hot water is more convenient. It has been reported previously that under certain conditions, dietary antioxidants such as ascorbic acid, tocopherol and carotenoids could act, occasionally, as pro-oxidants to initiate slight degree of oxidative stress microenvironment. statement and Manage cookies/Do not sell my data we use in the preference centre. Oyenihi OR, Brooks NL, Oguntibeju OO. There may be some problems if the air is too dry in winter. This is attributed to the anti-hyperlipidaemic properties of the plant. Justicia Carnea leaves extract contains a rich supply of iron, riboflavin, vitamins A, C, E, B1, B2, B9, and B12. Cardioprotective role of Justicia traquebareinsis Linn. There are several scientific studies which show that the methanolic leaf extract of Justicia carnea protects the liver from toxic effect of carbon tetrachloride harmful effect on the live integrity and functions. The ability of glutathione to regenerate these dietary antioxidants has been linked to the redox state of glutathione disulphide-glutathione couple (GSSG/GSH) ratio [31]. Superoxide dismutase (SOD) activities were elevated across all doses in the liver with significant (p<0.05) difference only observed in the highest dose (1200mg/kg) while kidney showed no significant difference compared to the control. Rats that received 50 and 100mg/kg body weight JCEE showed significant (p<0.05) increase in liver weight while other doses showed no significant difference compared to the control. Packed cell volume (PCV) and mean corpuscular volume (MCV) in treated rats with JCEE were statistically unperturbed compared to the control. In traditional medicine, justicia carnea is used in treating hepatitis. Note this is the default cart. 2019;30(4):64554. In this study, the aqueous leaf extract of Justicia carnea was used. It is commonly referred to as blood root, blood booster, ewe eje in Yoruba, Ogwu obara in Igbo, and jacobinia in Brazil and south America.The plant, which is usually green in color and produces pink flowers, belongs to the family of Acanthaceae. Haematological and biochemical studies on Justicia carnea leaves extract in phenylhydrazine induced-anemia in albino rats. hindawi publishing corporation evidence-based complementary and alternative medicine. In a reaction mixture containing 0.01M phosphate buffer (pH7.0), 0.5ml of 0.2M H2O2 and 0.4ml distilled water, 0.5ml of sample was added. The cuttings should be placed in individuals pots and put under glass or shaded location, away from direct sunlight. 3rd ed. Local consumers of the leaves are mostly . J Nat Prod 1988;51(4):804-805. This also helps prevent self-seeding, which normally takes up a lot of the plants energy at the expense of flowering. Be careful about the moisture in the soil, avoiding letting it dry completely. Relative to control, lymphocyte and granulocyte exhibited no significant difference in all doses while MID was elevated in treated groups with significant increase in rats administered with 500 and 800mg/kg body weight. 2016;4(1):5360. The plant, which is usually green in color and produces pink flowers, belongs to the family of Acanthaceae. I also conduct research on molecular basis of human diseases, linking the pharmacological properties of certain natural products and their mechanisms of actions to the treatment of such diseases. Phytochemical profile, antioxidant, -amylase inhibition, binding Olaniyan JM, Hadiza LM, Hussaini AM, Musa BB, Abubakar SA. The weight of organs (liver and kidney) reduced steadily in a concentration dependent manner. Effect of Tectona grandis on phenylhydrazine induced anemia in rats. Justicia carnea (Brazilian Plume) - Gardenia.net Sample (or standard solution) (0.01ml) was mixed with diluted (1:4v/v distilled water) biuret reagent (100mM sodium hydroxide, 16mM sodium-potassium tartrate, 15mM potassium iodide and 6mM copper sulphate). Safety assessment of oral administration of ethanol extract of Justicia Organic extract of Justicia pectoralis Jacq. Once the roots have established, adjust watering to three to five days apart. PDF Evaluation of Anti-inflammatory and Analgesic Properties of Justicia Anti-obesity, antioxidant and in silico evaluation of Justicia carnea Therefore,it is imperative to investigate the effects of the plant on the essential biochemical indices in diabetic rats so as to establish its safety. How long does it take for Aju mbaise to work. https://doi.org/10.35841/biomedicalresearch.30-18-666. View abstract. Leal, L. K., Ferreira, A. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Keep an eye out for glasshouse red spider mite and glasshouse whitefly. This lends the plant some interesting names such as Blood of Jesus plant and Hospital too far. SOD activity was determined by its ability to inhibit the auto-oxidation of epinephrine determined by the increase in absorbance at 480nm. Ewe eje or Ewe ajeri is known by the Igbo tribe as Ogwu obara. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. To create additional collections, you must be a paid member of our site. Justicia carnea, the Brazilian plume flower, Brazilian-plume, flamingo flower, or jacobinia, is a flowering plant in the family Acanthaceae. MacRae, W. D. and Towers, G. H. Justicia pectoralis: a study of the basis for its use as a hallucinogenic snuff ingredient. While the renal tubules across the tested groups were normal with the interstitial spaces showing moderate congestion and hemorrhage, there appeared some abnormalities in the renal cortex (such as few sclerotic glomeruli with moderately dilated capsular spaces) resulting in fair architectural structure of the kidney (Fig. Akintimehin, E.S., Karigidi, K.O., Omogunwa, T.S. Joseph, H., Gleye, J., Moulis, C., Fouraste, I., and Stanislas, E. O-Methoxylated C-glycosylflavones from Justicia pectoralis. The plant has various other common names including: Back in the day, the Justicia flower was boiled and used to solve anemia problems. The lush foliage and distinctive flowers make Brazilian Plume a natural for a tropical garden. In recent time, copious attention has been focused on the use of medicinal plants in the management and treatment of ailments such as anemia, diabetes and malaria. 2005 - 2023 WebMD LLC, an Internet Brands company. PDF Biomedical Research 2019; 30 (4): 645-654 ISSN 0970-938X - Allied Academies Niger J Physiol Sci. The unique and beautiful tubular flowers of Justicia carnea highlight the plant. Tags: benefits of justicia carnea, health benefit of justicia carnea, justicia carnea . The ameliorative effect of Justicia carnea on blood glucose level and lipid profile in alloxan-induced diabetic albino rats was evaluated in a study titled, "Effects of methanol leaves extract . Too much sun can scorch the leaves, and too little will result in fewer flowers. Macrocytic and hypochromic anemia usually results due to increased mean corpuscular volume (MCV) and decrease in mean corpuscular hemoglobin concentration [30]. Biochemistry Unit, Department of Chemical Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Nigeria, Emmanuel Sina Akintimehin,Kayode Olayele Karigidi,Tope Samuel Omogunwa&Foluso Olutope Adetuyi, You can also search for this author in It is cultivated and sold as a decorative potted plant and is planted in landscaping as a feature plant in warm . Different drugs are used but many depend mainly on plants and herbal products for its treatment. By entering your email address you agree to receive a daily email newsletter from Plant Care Today. Oral acute toxicity study on J. carnea ethanol extract (JCEE) was carried out according to Lorke [15] method using the total of twelve (12) albino rats in two phases. The leaves of justicia carnea possess high content of iron and vitamin C. This compounds may be responsible for the blood boosting property of ewe eje leaves. Justicia Carnea is a flowering plant that may be found in our neighborhood. The mixture was allowed to cool and centrifuged at 650g for 10min to obtain the supernatant. Dyslipidemia is one of the risk factors of cardiovascular diseases. Current School News Inhibitory Potential and Antidiabetic Activity of Leaf Extracts of Justicia carnea. J. Pharmacogn. The appropriate dose of Justicia pectoralis depends on several factors such as the user's age, health, and several other conditions. In Nigeria, the leaf of Justicia carnea is usually prepared with edible vegetables to make soup, boiled separately in water to make tea or prepared by cooking with other medicinal plants for therapeutic purposes. 2013;3(4):1248 https://doi.org/10.7324/JAPS.2013.3422. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. Authors TSO, KOK and ESA manage experimental protocols and performed the experiments under the supervision of FOA. He has B.Sc.,and M.Sc. Correspondence to Biomed Environ Mass Spectrom 1988;15(8):413-417. Radhika J, Sathya S, Jothi G, Japasheba JL. J Ethnopharmacol. Akintimehin is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. long (20 cm), densely packed with pink to crimson tubular flowers. Ewe eje as a Natural Blood booster/tonic: Due to the high concentration of iron in this leaf, it can help boost blood production by increasing the red blood cells, haemoglobin, and the blood platelets. But like in the case of depression and hepatitis, other species of justicia have been studied and proven to be antiepileptic. 2008; 10:2. When properly cooked with water, the leaf resembles blood, and when milk is added, it turns pink. Eyong EU, Umoh IB, Ebong PE, Eteng MU, Antai AB, Akpa AO. Pharm. The plants cannot be propagated with seeds. Nigeria's medicinal plant: Justicia carne (Ewe eje) - PressReader Justicia carnea does not cause miscarriage or congenital birth defects. Liver and kidney are the main targets of toxicants because they are respectively involved in biotransformation and excretion of xenobiotics. Justicia carnea is amedicinal plant used widely in Nigeria which is reported to have diverse functions, including blood-boosting potential. National Research Council. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. The animals were initially examined for any signs of toxicity after 60min of administration and further observed for a period of 24h. The absence of rat mortality in phase I necessitated the conduct of the second phase. The very tropical looking Brazilian plume with its bright inflorescence is definitely a unique addition to gardens. Diallo A, Gbeassor M, Vovor A, Eklu-Gadegbeku K, Aklikokou K, Agbonon A. 2015;174:61827 https://doi.org/10.1016/j.jep.2015.06.005. volume7, Articlenumber:2 (2021) These compounds beyond boosting your blood concentration, thereby enhancing the transport of nutrients to various parts of the body, also boost your immune system against several infectious diseases. The LD50 of extract was greater than 5000mg/kg body weight. One of the health benefits of justicia carnea is in boosting immune system. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. It may be, judging from the antidepressant activity of other plant of justicia species whose activity have been studied, proper to state that justicia carnea may possess antidepressant properties. Information from this source is evidence-based and objective, and without commercial influence. Effect of the ethanol extract of Justicia carnea leaves on the red PubMed Article Rats were further observed for extended hours of 48h to see if mortality would occur. In sub-acute toxicity study, total of thirty (30) rats were randomized into six groups of five rats per group: Group 1 served as control and was administered with 1ml of distilled water (dH2O). Microsomal lipid peroxidation. PubMedGoogle Scholar. Research reports it isn't capable of . Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. The renal effects of blood glucose-lowering plant-derived extracts in diabetes mellitus-an overview. The reaction is terminated by the addition of 2ml of dichromoacetic acid mixture (potassium dichromate (5%) and glacial acetic acid; 1:3v/v) and heated at 60C for 10min. https://doi.org/10.3390/molecules191221442. Studies have shown that ewe eje contains antioxidant and cardio-protective properties. OTHER NAME(S): Achille Millefeuille, Achille Mille-Feuille, Ana. degree in Biochemistry from Olabisi Onabanjo University, Ago-iwoye, and University of Ibadan, Ibadan, Nigeria respectively. The renal cortex showed normal glomeruli with mesangial cells and capsular spaces appeared normal (white arrow), the renal tubules appear normal (blue arrow) and interstitial spaces also observed normal (black arrow). McCune LM, Johns T. Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the indigenous peoples of the north American boreal forest. Biomed Res. The haematological indices of the blood samples were determined using an automated URIT 2900 Plus 3 Differential Haematological Analyzer. Clinical Guide to Laboratory tests. 2007;39(1):4484. It is a creeping, perennial plant and grows up to 2 meters tall. These antibodies help prevent infections and fight off diseases. https://doi.org/10.4314/njps.v19i1.32627. The perennial plant puts on a never-ending show of radiant flowers from early spring to fall. Powdered sample (1000g) was soaked in absolute ethanol (3000mL) with constant stirring. This plant is somewhat drought-tolerant once established but looks best with regular watering during periods of extended dry weather. Growing up, we were told many biblical stories, Negro pepper (Xylopia aethiopica) is a spice plant that possess several health benefits, which make it an indispensable, Eating for its sour taste when fairly ripen and sweet taste when well ripen, star apple finds favor, Fertility tree (Newbouldia laevis), also known as boundary tree, Ogirisi in Igbo, Adikuru in Hausa and Ewe akoko, Guava (Psidium guajava) is a well known tropical tree which is widely grown for its fruits. Ren Fail. The compound responsible for this activity is lignan. We currently have no information for JUSTICIA PECTORALIS overview. and M.Sc. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. Despite living in close proximity to this plant, many individuals may be unaware of its benefits. Side Effects, Uses and Health benefits of Ewe eje (Justicia carnea leaf), The exact topic of this article first appeared on www.nimedhealth.com.ng. Keep the soil moist, but not waterlogged. 2. However, serious caution of the dose should be taken into consideration when extrapolating this result for human consumption. He is a research assistant in the Biochemistry Unit of the same Department. Molecules (Basel, Switzerland), 19(12), 2144221461. Justicia Carnea Leaf Benefits - Ewe eje - besthomediet Joseph, H., Gleye, J., Moulis, C., Mensah, L. J., Roussakis, C., and Gratas, C. Justicidin B, a cytotoxic principle from Justicia pectoralis. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. Histopathological examination of liver and kidney showed mild to severe pathological lesion in a dose dependent manner. https://doi.org/10.1016/j.biocel.2006.07.001. Photomicrograph of a liver sections stained with Haematoxylin and Eosin (Mag. Duan WL, Liang XM. Corra, GM., de C. Alcntara, AF. It is an awesome plant and worth your time and attention. These tropical plants are not very fussy about soil. Decreased white blood cell count was obtained in this report, the level of lymphocyte and granulocyte was not altered by the extract while MID sized cell was significantly elevated at 500 and 800mg/kg dose. In conclusion, oral acute administration of J. carnea ethanol extract is safe because neither mortality nor any signs of toxicity were observed in experimental rats. Total reaction mixture of 3ml contained 2.95ml of 0.05M sodium carbonate buffer (pH10.2), 0.02ml tissue sample and 0.03ml of epinephrine (2mM) in 0.005N HCl was used to initiate the reaction. This may be because of its hepatoprotective activity. Pot the specimen and bring it indoors to add a bright touch of color to your interiors.